Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHOX2BPaired like homeobox 2B. (289 aa)    
Predicted Functional Partners:
PHOX2A
Paired like homeobox 2A.
   
 
 0.897
DBH
Dopamine beta-hydroxylase.
   
 
 0.795
ENSNVIP00000009764
annotation not available
   
  
 0.755
HAND2
Heart and neural crest derivatives expressed 2.
   
 
 0.722
LMX1B
LIM homeobox transcription factor 1 beta.
  
   
 0.705
SOX10
SRY-box transcription factor 10.
      
 0.695
GPR4
G protein-coupled receptor 4.
      
 0.651
ASCL1
Achaete-scute family bHLH transcription factor 1.
   
 
 0.635
IQCF5
IQ motif containing F5.
      
 0.620
ENSNVIP00000019820
Endothelin receptor type B.
      
 0.560
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.