TMEM50B protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

TMEM50B

Transmembrane protein 50B. (125 aa)

Predicted Functional Partners:

LEPROTL1

0.823

LEPROT

0.823

ENSNVIP00000023202

0.705

DONSON

0.559

MRPS6

0.558

ENSNVIP00000010292

0.555

ENSNVIP00000017227

0.555

SON

0.518

IGF2R

0.476

ENSNVIP00000030418

0.471

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DONSON	MRPS6	ENSNVIP00000007678	ENSNVIP00000008744	Downstream neighbor of SON.	Mitochondrial ribosomal protein S6.	0.730
DONSON	SON	ENSNVIP00000007678	ENSNVIP00000007584	Downstream neighbor of SON.	SON DNA binding protein.	0.560
DONSON	TMEM50B	ENSNVIP00000007678	ENSNVIP00000007356	Downstream neighbor of SON.	Transmembrane protein 50B.	0.559
ENSNVIP00000010292	ENSNVIP00000017227	ENSNVIP00000010292	ENSNVIP00000017227	annotation not available	annotation not available	0.999
ENSNVIP00000010292	ENSNVIP00000023202	ENSNVIP00000010292	ENSNVIP00000023202	annotation not available	annotation not available	0.974
ENSNVIP00000010292	TMEM50B	ENSNVIP00000010292	ENSNVIP00000007356	annotation not available	Transmembrane protein 50B.	0.555
ENSNVIP00000017227	ENSNVIP00000010292	ENSNVIP00000017227	ENSNVIP00000010292	annotation not available	annotation not available	0.999
ENSNVIP00000017227	ENSNVIP00000023202	ENSNVIP00000017227	ENSNVIP00000023202	annotation not available	annotation not available	0.972
ENSNVIP00000017227	TMEM50B	ENSNVIP00000017227	ENSNVIP00000007356	annotation not available	Transmembrane protein 50B.	0.555
ENSNVIP00000023202	ENSNVIP00000010292	ENSNVIP00000023202	ENSNVIP00000010292	annotation not available	annotation not available	0.974
ENSNVIP00000023202	ENSNVIP00000017227	ENSNVIP00000023202	ENSNVIP00000017227	annotation not available	annotation not available	0.972
ENSNVIP00000023202	TMEM50B	ENSNVIP00000023202	ENSNVIP00000007356	annotation not available	Transmembrane protein 50B.	0.705
ENSNVIP00000030418	TMEM50B	ENSNVIP00000030418	ENSNVIP00000007356	annotation not available	Transmembrane protein 50B.	0.471
IGF2R	TMEM50B	ENSNVIP00000013382	ENSNVIP00000007356	Insulin like growth factor 2 receptor.	Transmembrane protein 50B.	0.476
LEPROT	TMEM50B	ENSNVIP00000013482	ENSNVIP00000007356	Leptin receptor overlapping transcript.	Transmembrane protein 50B.	0.823
LEPROTL1	TMEM50B	ENSNVIP00000008348	ENSNVIP00000007356	Leptin receptor overlapping transcript like 1.	Transmembrane protein 50B.	0.823
MRPS6	DONSON	ENSNVIP00000008744	ENSNVIP00000007678	Mitochondrial ribosomal protein S6.	Downstream neighbor of SON.	0.730
MRPS6	SON	ENSNVIP00000008744	ENSNVIP00000007584	Mitochondrial ribosomal protein S6.	SON DNA binding protein.	0.591
MRPS6	TMEM50B	ENSNVIP00000008744	ENSNVIP00000007356	Mitochondrial ribosomal protein S6.	Transmembrane protein 50B.	0.558
SON	DONSON	ENSNVIP00000007584	ENSNVIP00000007678	SON DNA binding protein.	Downstream neighbor of SON.	0.560