Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEP57Centrosomal protein 57. (502 aa)    
Predicted Functional Partners:
CEP63
Centrosomal protein 63.
   
 
 0.939
DEUP1
Deuterosome assembly protein 1.
   
 
 0.902
PLK1
Polo like kinase 1.
     
 0.761
TRIP13
Thyroid hormone receptor interactor 13.
   
  
 0.704
CEP290
Centrosomal protein 290.
   
 0.607
MAPRE1
Microtubule associated protein RP/EB family member 1.
      
 0.573
NDEL1
nudE neurodevelopment protein 1 like 1.
     
 0.551
CEP135
Centrosomal protein 135.
   
 
 0.548
POC1B
POC1 centriolar protein B.
   
 
 0.546
CEP192
Centrosomal protein 192.
   
 
 0.532
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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