Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DACT1Dishevelled binding antagonist of beta catenin 1. (841 aa)    
Predicted Functional Partners:
DVL2
Dishevelled segment polarity protein 2.
    
 0.975
DVL1
Dishevelled segment polarity protein 1.
    
 0.968
DVL3
Dishevelled segment polarity protein 3.
    
 0.952
VANGL2
VANGL planar cell polarity protein 2.
    
 
 0.851
ENSNVIP00000009648
SEC14 and spectrin domain containing 1.
    
 
 0.824
VANGL1
VANGL planar cell polarity protein 1.
    
 
 0.800
KIAA0586
KIAA0586.
      
 0.706
ENSNVIP00000031759
Catenin beta 1.
    
 0.673
HDAC2
Histone deacetylase 2.
    
 
 0.574
ENSNVIP00000009507
annotation not available
    
 
 0.574
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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