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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AQP2Aquaporin 2. (271 aa)    
Predicted Functional Partners:
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
   
 
 0.881
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
   
 
 0.881
ENSNVIP00000000557
annotation not available
  
  
0.746
GPD2
Glycerol-3-phosphate dehydrogenase 2.
  
  
 0.721
ENSNVIP00000001011
Aquaporin 11.
     
 0.715
ENSNVIP00000000969
Aquaporin 9.
  
  
0.697
AQP10
Aquaporin 10.
  
  
0.690
ENSNVIP00000000217
annotation not available
   
  
 0.668
AGT
Angiotensinogen.
      
 0.622
SFTPC
Pulmonary surfactant-associated protein C.
   
  
 0.576
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.