Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
RAC1Rac family small GTPase 1. (185 aa)    
Predicted Functional Partners:
PREX1
Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1.
    
 0.963
CYBA
Cytochrome b-245 alpha chain.
   
 0.951
NCF1
Neutrophil cytosolic factor 1.
   
 0.947
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.944
ENSNVIP00000004207
annotation not available
   
 0.935
NCKAP1
NCK associated protein 1.
   
 0.935
PAK2
P21 (RAC1) activated kinase 2.
   
 0.932
ENSNVIP00000015599
Neutrophil cytosolic factor 2.
   
 0.931
TIAM1
TIAM Rac1 associated GEF 1.
    
 0.927
PIK3CB
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
   
 0.925
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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