Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIDD1P53-induced death domain protein 1. (915 aa)    
Predicted Functional Partners:
CASP2
Caspase 2.
    
 0.995
ENSNVIP00000008759
annotation not available
    
 0.978
ENSNVIP00000008764
CASP2 and RIPK1 domain containing adaptor with death domain.
    
 0.978
ATM
ATM serine/threonine kinase.
    
 0.928
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.875
WDR90
WD repeat domain 90.
   
 0.851
FADD
Fas associated via death domain.
   
 0.829
ENSNVIP00000016365
annotation not available
    
 0.808
ENSNVIP00000029921
annotation not available
    
 0.808
TONSL
Tonsoku like, DNA repair protein.
   
 0.795
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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