Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AFAP1Actin filament associated protein 1. (812 aa)    
Predicted Functional Partners:
ANLN
Anillin actin binding protein.
    
 
 0.741
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
    
 
 0.675
YES1
YES proto-oncogene 1, Src family tyrosine kinase.
    
 
 0.675
GADD45G
Growth arrest and DNA damage inducible gamma.
    
   0.628
GMDS
GDP-mannose 4,6-dehydratase.
      
 0.518
TMCO1
Transmembrane and coiled-coil domains 1.
      
 0.511
SH3TC1
SH3 domain and tetratricopeptide repeats 1.
      
 0.506
ACTL7A
Actin like 7A.
    
 
 0.504
MAGED1
MAGE family member D1.
      
 0.488
ABLIM2
Actin binding LIM protein family member 2.
      
 0.488
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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