Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HFEHomeostatic iron regulator. (356 aa)    
Predicted Functional Partners:
TFRC
Transferrin receptor.
    
 0.998
TFR2
Transferrin receptor 2.
    
 0.997
HJV
Hemojuvelin BMP co-receptor.
     
 0.979
B2M
Beta-2-microglobulin.
   
 0.887
EPO
Erythropoietin.
    
 0.880
RPA2
Replication protein A2.
   
 0.831
RGMB
Repulsive guidance molecule BMP co-receptor b.
     
 0.785
RGMA
Repulsive guidance molecule BMP co-receptor a.
     
 0.785
HAMP
Hepcidin antimicrobial peptide.
   
  
 0.758
TMPRSS6
Transmembrane serine protease 6.
     
 0.655
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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