Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLR3Toll like receptor 3. (871 aa)    
Predicted Functional Partners:
TICAM1
Toll like receptor adaptor molecule 1.
    
 0.985
UNC93B1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.983
ENSNVIP00000013359
TNF receptor associated factor 6.
   
 0.978
RIPK1
Receptor interacting serine/threonine kinase 1.
    
 0.975
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.960
MYD88
MYD88 innate immune signal transduction adaptor.
    
 0.960
TRAF3
TNF receptor associated factor 3.
   
 0.957
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.956
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.955
TBK1
TANK binding kinase 1.
   
 0.943
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.