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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR3Toll like receptor 3. (871 aa)    
Predicted Functional Partners:
TICAM1
Toll like receptor adaptor molecule 1.
   
 0.991
ENSNVIP00000013359
TNF receptor associated factor 6.
   
 0.988
UNC93B1
Unc-93 homolog B1, TLR signaling regulator.
    
 0.984
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.977
RIPK1
Receptor interacting serine/threonine kinase 1.
   
 0.973
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.963
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
    
 0.960
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.958
LY96
Lymphocyte antigen 96.
   
 0.860
TICAM2
Toll like receptor adaptor molecule 2.
   
 0.856
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.