Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)    
Predicted Functional Partners:
PPM1N
Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative).
   
   0.956
ENSNVIP00000021265
annotation not available
   
   0.956
MAP2K4
Mitogen-activated protein kinase kinase 4.
    
 0.910
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
  0.893
MAP2K3
Mitogen-activated protein kinase kinase 3.
    
  0.891
MAP2K6
Mitogen-activated protein kinase kinase 6.
    
  0.891
SMAD2
SMAD family member 2.
   
 0.752
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.745
SMAD4
SMAD family member 4.
   
 0.739
SMAD3
SMAD family member 3.
   
 0.732
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.