Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIX6SIX homeobox 6. (246 aa)    
Predicted Functional Partners:
TLE1
TLE family member 1, transcriptional corepressor.
    
 
 0.681
NR4A3
Nuclear receptor subfamily 4 group A member 3.
    
 
 0.673
VAX2
Ventral anterior homeobox 2.
   
 
 0.592
PAX6
Paired box 6.
   
 
 0.559
LRRC9
Leucine rich repeat containing 9.
    
 
 0.554
EYA2
EYA transcriptional coactivator and phosphatase 2.
   
 0.536
EYA1
EYA transcriptional coactivator and phosphatase 1.
   
 0.536
EYA4
EYA transcriptional coactivator and phosphatase 4.
   
 0.536
EYA3
EYA transcriptional coactivator and phosphatase 3.
   
 0.536
CNGA3
Cyclic nucleotide gated channel subunit alpha 3.
      
 0.534
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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