Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIX4SIX homeobox 4. (784 aa)    
Predicted Functional Partners:
EYA2
EYA transcriptional coactivator and phosphatase 2.
   
 0.840
EYA3
EYA transcriptional coactivator and phosphatase 3.
   
 0.835
EYA1
EYA transcriptional coactivator and phosphatase 1.
   
 0.806
EYA4
EYA transcriptional coactivator and phosphatase 4.
   
 0.740
PAX8
Paired box 8.
    
 0.634
PAX5
Paired box 5.
    
 0.570
PAX2
Paired box 2.
    
 0.570
EMX2
Empty spiracles homeobox 2.
  
 
 0.526
ENSNVIP00000025437
Distal-less homeobox 5.
   
  
 0.497
HOXA5
Homeobox A5.
    
 
 0.489
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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