Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRG1Neuregulin 1. (712 aa)    
Predicted Functional Partners:
ERBB2
Erb-b2 receptor tyrosine kinase 2.
    
 0.996
ERBB3
Erb-b2 receptor tyrosine kinase 3.
    
 0.994
ERBB4
Erb-b2 receptor tyrosine kinase 4.
    
 0.992
EGFR
Epidermal growth factor receptor.
    
 0.992
NRG2
Neuregulin 2.
     
 0.897
NRG3
Neuregulin 3.
     
 0.886
EGF
Epidermal growth factor.
    
 0.774
BDNF
Brain derived neurotrophic factor.
      
 0.726
NGF
Nerve growth factor.
      
 0.720
EREG
Epiregulin.
    
 0.693
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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