Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPDL1Spindle apparatus coiled-coil protein 1. (556 aa)    
Predicted Functional Partners:
PLK1
Polo like kinase 1.
   
 
 0.904
ENSNVIP00000003468
Centrosomal protein 55.
   
  
 0.836
NUDC
Nuclear distribution C, dynein complex regulator.
     
  0.786
CKAP2L
Cytoskeleton associated protein 2 like.
   
    0.751
NDC80
NDC80 kinetochore complex component.
   
 
 0.741
ENSNVIP00000020897
annotation not available
   
 
 0.725
CDC20B
Cell division cycle 20B.
   
 
  0.703
CDC20
Cell division cycle 20.
   
 
  0.703
ENSNVIP00000021628
NUF2 component of NDC80 kinetochore complex.
   
 
 0.676
SF3B3
Splicing factor 3b subunit 3.
    
   0.628
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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