FAM117A protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FAM117A

Family with sequence similarity 117 member A. (412 aa)

Predicted Functional Partners:

DYRK1A

0.678

AGO2

0.642

ENSNVIP00000010888

0.559

SLC4A9

0.491

TSC22D2

0.484

DCAF7

0.484

ENSNVIP00000013778

0.480

PKIA

0.476

SLC35B1

0.466

FAM102B

0.441

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	FAM117A	ENSNVIP00000020085	ENSNVIP00000008377	Argonaute RISC catalytic component 2.	Family with sequence similarity 117 member A.	0.642
DCAF7	DYRK1A	ENSNVIP00000030305	ENSNVIP00000021125	DDB1 and CUL4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 1A.	0.973
DCAF7	ENSNVIP00000013778	ENSNVIP00000030305	ENSNVIP00000013778	DDB1 and CUL4 associated factor 7.	Dual specificity tyrosine phosphorylation regulated kinase 1B.	0.969
DCAF7	FAM117A	ENSNVIP00000030305	ENSNVIP00000008377	DDB1 and CUL4 associated factor 7.	Family with sequence similarity 117 member A.	0.484
DYRK1A	DCAF7	ENSNVIP00000021125	ENSNVIP00000030305	Dual specificity tyrosine phosphorylation regulated kinase 1A.	DDB1 and CUL4 associated factor 7.	0.973
DYRK1A	ENSNVIP00000013778	ENSNVIP00000021125	ENSNVIP00000013778	Dual specificity tyrosine phosphorylation regulated kinase 1A.	Dual specificity tyrosine phosphorylation regulated kinase 1B.	0.893
DYRK1A	FAM117A	ENSNVIP00000021125	ENSNVIP00000008377	Dual specificity tyrosine phosphorylation regulated kinase 1A.	Family with sequence similarity 117 member A.	0.678
ENSNVIP00000010888	FAM102B	ENSNVIP00000010888	ENSNVIP00000018528	GRB2 binding adaptor protein, transmembrane.	Family with sequence similarity 102 member B.	0.593
ENSNVIP00000010888	FAM117A	ENSNVIP00000010888	ENSNVIP00000008377	GRB2 binding adaptor protein, transmembrane.	Family with sequence similarity 117 member A.	0.559
ENSNVIP00000010888	PKIA	ENSNVIP00000010888	ENSNVIP00000018989	GRB2 binding adaptor protein, transmembrane.	cAMP-dependent protein kinase inhibitor alpha.	0.524
ENSNVIP00000010888	SLC4A9	ENSNVIP00000010888	ENSNVIP00000017881	GRB2 binding adaptor protein, transmembrane.	Solute carrier family 4 member 9.	0.492
ENSNVIP00000013778	DCAF7	ENSNVIP00000013778	ENSNVIP00000030305	Dual specificity tyrosine phosphorylation regulated kinase 1B.	DDB1 and CUL4 associated factor 7.	0.969
ENSNVIP00000013778	DYRK1A	ENSNVIP00000013778	ENSNVIP00000021125	Dual specificity tyrosine phosphorylation regulated kinase 1B.	Dual specificity tyrosine phosphorylation regulated kinase 1A.	0.893
ENSNVIP00000013778	FAM117A	ENSNVIP00000013778	ENSNVIP00000008377	Dual specificity tyrosine phosphorylation regulated kinase 1B.	Family with sequence similarity 117 member A.	0.480
FAM102B	ENSNVIP00000010888	ENSNVIP00000018528	ENSNVIP00000010888	Family with sequence similarity 102 member B.	GRB2 binding adaptor protein, transmembrane.	0.593
FAM102B	FAM117A	ENSNVIP00000018528	ENSNVIP00000008377	Family with sequence similarity 102 member B.	Family with sequence similarity 117 member A.	0.441
FAM102B	PKIA	ENSNVIP00000018528	ENSNVIP00000018989	Family with sequence similarity 102 member B.	cAMP-dependent protein kinase inhibitor alpha.	0.510
FAM102B	SLC4A9	ENSNVIP00000018528	ENSNVIP00000017881	Family with sequence similarity 102 member B.	Solute carrier family 4 member 9.	0.512
FAM117A	AGO2	ENSNVIP00000008377	ENSNVIP00000020085	Family with sequence similarity 117 member A.	Argonaute RISC catalytic component 2.	0.642
FAM117A	DCAF7	ENSNVIP00000008377	ENSNVIP00000030305	Family with sequence similarity 117 member A.	DDB1 and CUL4 associated factor 7.	0.484