STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRK1Leucine rich repeat kinase 1. (2010 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.896
BAG5
BCL2 associated athanogene 5.
    
   0.838
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase.
   
  0.831
LRRK2
Leucine rich repeat kinase 2.
    
 0.691
EGFR
Epidermal growth factor receptor.
    
 0.690
SHC3
SHC adaptor protein 3.
    
   0.669
SHC1
SHC adaptor protein 1.
    
   0.669
BAG2
BCL2 associated athanogene 2.
    
 
 0.658
VGLL4
Vestigial like family member 4.
    
 
 0.656
PAK6
P21 (RAC1) activated kinase 6.
    
 0.652
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.