Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABRABR activator of RhoGEF and GTPase. (964 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 0.959
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.924
CRK
CRK proto-oncogene, adaptor protein.
    
 0.881
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase.
    
 0.873
ABL1
ABL proto-oncogene 1, non-receptor tyrosine kinase.
    
 0.873
CBL
Cbl proto-oncogene.
    
 0.793
CBLB
Cbl proto-oncogene B.
    
 0.793
SHC4
SHC adaptor protein 4.
     
 0.755
KIT
KIT proto-oncogene, receptor tyrosine kinase.
    
 0.754
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.
    
 0.722
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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