Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSNVIP00000008462Sterile alpha motif domain containing 12. (195 aa)    
Predicted Functional Partners:
CNKSR2
Connector enhancer of kinase suppressor of Ras 2.
    
 0.927
IPCEF1
Interaction protein for cytohesin exchange factors 1.
    
 0.859
CNKSR3
CNKSR family member 3.
    
 0.859
CNKSR1
Connector enhancer of kinase suppressor of Ras 1.
    
 0.769
KSR2
Kinase suppressor of ras 2.
    
 0.709
KSR1
Kinase suppressor of ras 1.
    
 0.709
ENSNVIP00000009250
annotation not available
    
  0.588
ENSNVIP00000020519
Mitogen-activated protein kinase kinase 5.
    
  0.588
MAP2K1
Mitogen-activated protein kinase kinase 1.
    
  0.588
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 0.511
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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