Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HIF1AHypoxia inducible factor 1 subunit alpha. (823 aa)    
Predicted Functional Partners:
EP300
E1A binding protein p300.
    
 0.995
CUL2
Cullin 2.
    
 0.995
ELOB
Elongin B.
    
 0.995
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor.
    
 0.994
CREBBP
CREB binding protein.
    
 0.994
VHL
Von Hippel-Lindau tumor suppressor.
    
 0.993
ARNT2
Aryl hydrocarbon receptor nuclear translocator 2.
   
 0.987
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
 0.987
EGLN3
Egl-9 family hypoxia inducible factor 3.
    
 0.974
TP53
Tumor protein p53.
    
 
 0.974
Your Current Organism:
Neovison vison
NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink
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