PLEKHG1 protein (Neovison vison) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PLEKHG1

Pleckstrin homology and RhoGEF domain containing G1. (1385 aa)

Predicted Functional Partners:

EP300

0.674

ENSNVIP00000024744

0.668

ENSNVIP00000003529

0.626

CDC42

0.626

ENSNVIP00000030096

0.626

ENSNVIP00000008397

0.612

RAC2

0.611

RAC1

0.611

RAC3

0.611

RHOV

0.611

Your Current Organism:

Neovison vison

NCBI taxonomy Id: 452646
Other names: American mink, Mustela vison, N. vison, mink

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	ENSNVIP00000024744	ENSNVIP00000029236	ENSNVIP00000024744	Cell division cycle 42.	Ras homolog family member G.	0.616
CDC42	PLEKHG1	ENSNVIP00000029236	ENSNVIP00000008492	Cell division cycle 42.	Pleckstrin homology and RhoGEF domain containing G1.	0.626
CDC42	RAC1	ENSNVIP00000029236	ENSNVIP00000007750	Cell division cycle 42.	Rac family small GTPase 1.	0.792
CDC42	RAC2	ENSNVIP00000029236	ENSNVIP00000003849	Cell division cycle 42.	Rac family small GTPase 2.	0.837
CDC42	RAC3	ENSNVIP00000029236	ENSNVIP00000021542	Cell division cycle 42.	Rac family small GTPase 3.	0.780
CDC42	RHOV	ENSNVIP00000029236	ENSNVIP00000021938	Cell division cycle 42.	Ras homolog family member V.	0.497
ENSNVIP00000003529	ENSNVIP00000024744	ENSNVIP00000003529	ENSNVIP00000024744	annotation not available	Ras homolog family member G.	0.616
ENSNVIP00000003529	PLEKHG1	ENSNVIP00000003529	ENSNVIP00000008492	annotation not available	Pleckstrin homology and RhoGEF domain containing G1.	0.626
ENSNVIP00000003529	RAC1	ENSNVIP00000003529	ENSNVIP00000007750	annotation not available	Rac family small GTPase 1.	0.792
ENSNVIP00000003529	RAC2	ENSNVIP00000003529	ENSNVIP00000003849	annotation not available	Rac family small GTPase 2.	0.837
ENSNVIP00000003529	RAC3	ENSNVIP00000003529	ENSNVIP00000021542	annotation not available	Rac family small GTPase 3.	0.780
ENSNVIP00000003529	RHOV	ENSNVIP00000003529	ENSNVIP00000021938	annotation not available	Ras homolog family member V.	0.497
ENSNVIP00000008397	PLEKHG1	ENSNVIP00000008397	ENSNVIP00000008492	Iodotyrosine deiodinase.	Pleckstrin homology and RhoGEF domain containing G1.	0.612
ENSNVIP00000024744	CDC42	ENSNVIP00000024744	ENSNVIP00000029236	Ras homolog family member G.	Cell division cycle 42.	0.616
ENSNVIP00000024744	ENSNVIP00000003529	ENSNVIP00000024744	ENSNVIP00000003529	Ras homolog family member G.	annotation not available	0.616
ENSNVIP00000024744	ENSNVIP00000030096	ENSNVIP00000024744	ENSNVIP00000030096	Ras homolog family member G.	annotation not available	0.616
ENSNVIP00000024744	PLEKHG1	ENSNVIP00000024744	ENSNVIP00000008492	Ras homolog family member G.	Pleckstrin homology and RhoGEF domain containing G1.	0.668
ENSNVIP00000024744	RAC1	ENSNVIP00000024744	ENSNVIP00000007750	Ras homolog family member G.	Rac family small GTPase 1.	0.773
ENSNVIP00000024744	RAC2	ENSNVIP00000024744	ENSNVIP00000003849	Ras homolog family member G.	Rac family small GTPase 2.	0.773
ENSNVIP00000024744	RAC3	ENSNVIP00000024744	ENSNVIP00000021542	Ras homolog family member G.	Rac family small GTPase 3.	0.773