STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A109UXM5Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (224 aa)    
Predicted Functional Partners:
A0A109UX27
HBR184Wp.
   
 0.940
A0A0X8HST4
Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
   
 0.904
A0A120K1C2
HBR300Wp.
     
 0.856
A0A109UYU0
Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.
     
 0.828
A0A120K1P1
Elongation of fatty acids protein.
   
 0.760
AW171_hschr231
Elongation of fatty acids protein.
   
 0.741
A0A120K1U7
HCL392Cp; Belongs to the SKP1 family.
    
 
 0.536
A0A109UWI2
HBL044Cp.
    
 
 0.530
A0A109UW66
HBL252Cp.
    
 
 0.478
A0A0X8HV16
HGL340Cp.
   
 
 0.443
Your Current Organism:
Eremothecium sinecaudum
NCBI taxonomy Id: 45286
Other names: ATCC 58844, CBS 8199, CCRC 21344, CCRC:21344, DAOM 187446, E. sinecaudum, Eremothecium sinecaudum (Holley) Kurtzman, Holleya sinecauda, NRRL Y-17231, Nematospora sinecauda
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