STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0E0NNN0Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (531 aa)    
Predicted Functional Partners:
A0A0E0QBB3
Pterin-binding domain-containing protein.
  
 
 0.962
A0A0E0R8F8
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family.
     
 0.959
A0A0E0RGW7
DHFR domain-containing protein.
     
 0.959
A0A0E0PPZ9
Folate gamma-glutamyl hydrolase.
     
 0.957
A0A0E0RK86
Mur_ligase_M domain-containing protein.
  
  
0.950
A0A0E0R120
Uncharacterized protein.
  
  
 
0.932
A0A0E0PTP7
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.902
A0A0E0QM96
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
  
 
 0.902
A0A0E0QS41
Uncharacterized protein.
  
 
 0.892
A0A0E0PEA5
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.811
Your Current Organism:
Oryza rufipogon
NCBI taxonomy Id: 4529
Other names: O. rufipogon, Oryza rufipogon Griff., common wild rice, red rice
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