Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lfee_0056Glutamine amidotransferase, class I. (233 aa)    
Predicted Functional Partners:
eutG
Alcohol dehydrogenase.
 
   
 0.885
gapN
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
     0.869
puuA
Glutamine synthetase.
 
   
 0.866
guaC
Inosine 5'-monophosphate dehydrogenase.
  
 
 0.680
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.680
Lfee_0057
SMP-30/Gluconolaconase/LRE-like region.
       0.671
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
 
 0.657
rplK
50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
    0.656
argS
arginyl-tRNA synthetase.
   
  
 0.649
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.616
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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