Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kynBMetal-dependent hydrolase. (231 aa)    
Predicted Functional Partners:
csaA
Chaperonin CsaA.
       0.789
cfiA_1
Oxaloacetate decarboxylase subunit alpha.
    
  0.755
fmdA
Amidase.
  
  
  0.621
capD
Nucleoside-diphosphate sugar epimerase.
       0.548
yieF
Chromate reductase, Class I, flavoprotein.
    
  0.500
Lfee_0766
Putative hydrolase.
    
  0.476
fadH
2,4-dienoyl-CoA reductase FadH1.
    
  0.476
ratA
Oligoketide cyclase/lipid transporter protein.
    
  0.462
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
     
  0.461
accC_1
Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
     
  0.461
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: low (24%) [HD]