Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tcmNO-methyltransferase. (332 aa)    
Predicted Functional Partners:
yhdE
Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
 
      0.900
Lfee_0197
General secretion pathway protein C.
       0.753
Lfee_0198
Sel-1 protein.
       0.753
pksJ
Polyketide synthase module.
 
  
 0.705
tycC_2
Peptide synthetase, non-ribosomal.
    
 0.667
Lfee_1859
Polyketide synthase module.
  
  
 0.574
Lfee_1201
Ankyrin repeat protein.
  
     0.567
Lfee_0013
Oxidoreductase.
  
  
 0.556
Lfee_2374
Acetyltransferase.
    
 0.552
tycC_1
Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.539
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: medium (42%) [HD]