garR_1 protein (Legionella feeleii) - STRING interaction network

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Score

garR_1

3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (299 aa)

Predicted Functional Partners:

Lfee_0373

0.994

mmsA

0.983

acsB

0.978

calB

0.856

gbsA

0.850

prpC

0.849

odp

0.848

gabT

0.812

nfi

0.732

Lfee_0762

0.725

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0373	Lfee_0762	Lfee_0373	Lfee_0762	Enoyl-CoA hydratase/carnithine racemase.	Acetyl/propionyl-CoA carboxylase, beta subunit.	0.582
Lfee_0373	garR_1	Lfee_0373	Lfee_0237	Enoyl-CoA hydratase/carnithine racemase.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.994
Lfee_0762	Lfee_0373	Lfee_0762	Lfee_0373	Acetyl/propionyl-CoA carboxylase, beta subunit.	Enoyl-CoA hydratase/carnithine racemase.	0.582
Lfee_0762	acsB	Lfee_0762	Lfee_0236	Acetyl/propionyl-CoA carboxylase, beta subunit.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.588
Lfee_0762	gabT	Lfee_0762	Lfee_1562	Acetyl/propionyl-CoA carboxylase, beta subunit.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.461
Lfee_0762	garR_1	Lfee_0762	Lfee_0237	Acetyl/propionyl-CoA carboxylase, beta subunit.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.725
Lfee_0762	odp	Lfee_0762	Lfee_3081	Acetyl/propionyl-CoA carboxylase, beta subunit.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.463
Lfee_0762	prpC	Lfee_0762	Lfee_3118	Acetyl/propionyl-CoA carboxylase, beta subunit.	2-methylcitrate synthase; Belongs to the citrate synthase family.	0.499
acsB	Lfee_0762	Lfee_0236	Lfee_0762	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Acetyl/propionyl-CoA carboxylase, beta subunit.	0.588
acsB	calB	Lfee_0236	Lfee_0510	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.859
acsB	gabT	Lfee_0236	Lfee_1562	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.853
acsB	garR_1	Lfee_0236	Lfee_0237	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.978
acsB	gbsA	Lfee_0236	Lfee_1561	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Glycine betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.854
acsB	mmsA	Lfee_0236	Lfee_0238	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Methylmalonate-semialdehyde dehydrogenase.	0.963
acsB	nfi	Lfee_0236	Lfee_0235	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Endonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.	0.732
acsB	odp	Lfee_0236	Lfee_3081	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.848
acsB	prpC	Lfee_0236	Lfee_3118	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-methylcitrate synthase; Belongs to the citrate synthase family.	0.893
calB	acsB	Lfee_0510	Lfee_0236	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.859
calB	gabT	Lfee_0510	Lfee_1562	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.653
calB	garR_1	Lfee_0510	Lfee_0237	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.856