mmsA protein (Legionella feeleii) - STRING interaction network

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Score

mmsA

Methylmalonate-semialdehyde dehydrogenase. (499 aa)

Predicted Functional Partners:

garR_1

0.922

acsB

0.870

korA

0.809

pksJ

0.807

pta

0.801

Lfee_0974

0.795

tycC_2

0.794

Lfee_2374

0.793

fadH

0.792

tycC_1

0.786

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0974	acsB	Lfee_0974	Lfee_0236	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.686
Lfee_0974	fadH	Lfee_0974	Lfee_2121	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	2,4-dienoyl-CoA reductase FadH1.	0.792
Lfee_0974	korA	Lfee_0974	Lfee_2569	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.406
Lfee_0974	mmsA	Lfee_0974	Lfee_0238	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Methylmalonate-semialdehyde dehydrogenase.	0.795
Lfee_0974	pksJ	Lfee_0974	Lfee_0647	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Polyketide synthase module.	0.450
Lfee_0974	tycC_1	Lfee_0974	Lfee_0391	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.	0.808
Lfee_0974	tycC_2	Lfee_0974	Lfee_0691	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Peptide synthetase, non-ribosomal.	0.808
Lfee_2374	acsB	Lfee_2374	Lfee_0236	Acetyltransferase.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.889
Lfee_2374	fadH	Lfee_2374	Lfee_2121	Acetyltransferase.	2,4-dienoyl-CoA reductase FadH1.	0.826
Lfee_2374	korA	Lfee_2374	Lfee_2569	Acetyltransferase.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.747
Lfee_2374	mmsA	Lfee_2374	Lfee_0238	Acetyltransferase.	Methylmalonate-semialdehyde dehydrogenase.	0.793
Lfee_2374	pksJ	Lfee_2374	Lfee_0647	Acetyltransferase.	Polyketide synthase module.	0.999
Lfee_2374	pta	Lfee_2374	Lfee_3110	Acetyltransferase.	Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.830
Lfee_2374	tycC_1	Lfee_2374	Lfee_0391	Acetyltransferase.	Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.	0.999
Lfee_2374	tycC_2	Lfee_2374	Lfee_0691	Acetyltransferase.	Peptide synthetase, non-ribosomal.	0.999
acsB	Lfee_0974	Lfee_0236	Lfee_0974	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.686
acsB	Lfee_2374	Lfee_0236	Lfee_2374	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Acetyltransferase.	0.889
acsB	fadH	Lfee_0236	Lfee_2121	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2,4-dienoyl-CoA reductase FadH1.	0.673
acsB	garR_1	Lfee_0236	Lfee_0237	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.910
acsB	korA	Lfee_0236	Lfee_2569	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.836