mmsA protein (Legionella feeleii) - STRING interaction network

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Score

mmsA

Methylmalonate-semialdehyde dehydrogenase. (499 aa)

Predicted Functional Partners:

garR_1

0.983

acsB

0.963

gabT

0.915

calB

0.881

korA

0.879

pta

0.869

prpC

0.858

atoB

0.852

yfcY

0.852

pcaF

0.852

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acsB	atoB	Lfee_0236	Lfee_0760	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.867
acsB	calB	Lfee_0236	Lfee_0510	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.859
acsB	gabT	Lfee_0236	Lfee_1562	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.853
acsB	garR_1	Lfee_0236	Lfee_0237	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.978
acsB	korA	Lfee_0236	Lfee_2569	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.928
acsB	mmsA	Lfee_0236	Lfee_0238	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Methylmalonate-semialdehyde dehydrogenase.	0.963
acsB	pcaF	Lfee_0236	Lfee_3049	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.867
acsB	prpC	Lfee_0236	Lfee_3118	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-methylcitrate synthase; Belongs to the citrate synthase family.	0.893
acsB	pta	Lfee_0236	Lfee_3110	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.925
acsB	yfcY	Lfee_0236	Lfee_2059	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	beta-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.867
atoB	acsB	Lfee_0760	Lfee_0236	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.867
atoB	korA	Lfee_0760	Lfee_2569	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.879
atoB	mmsA	Lfee_0760	Lfee_0238	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Methylmalonate-semialdehyde dehydrogenase.	0.852
atoB	pcaF	Lfee_0760	Lfee_3049	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.877
atoB	prpC	Lfee_0760	Lfee_3118	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	2-methylcitrate synthase; Belongs to the citrate synthase family.	0.866
atoB	pta	Lfee_0760	Lfee_3110	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.	0.891
atoB	yfcY	Lfee_0760	Lfee_2059	Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	beta-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.883
calB	acsB	Lfee_0510	Lfee_0236	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.859
calB	gabT	Lfee_0510	Lfee_1562	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.653
calB	garR_1	Lfee_0510	Lfee_0237	Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.856