STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqsAAntitoxin MqsA. (1353 aa)    
Predicted Functional Partners:
pksJ
Polyketide synthase module.
   
 
 0.523
yfcX
Enoyl CoA hydratase; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.499
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.499
Lfee_2688
Acyl dehydratase MaoC.
    
 0.492
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  0.466
sucC
Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
  0.447
prpD
2-methylcitrate dehydratase.
  
 
  0.442
pta
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.431
ribF
Riboflavin biosynthesis protein RibF (riboflavin kinase/FMN adenylyltransferase); Belongs to the ribF family.
   
 
  0.405
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.