Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
tycC_1Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family. (1435 aa)    
Predicted Functional Partners:
Lfee_1859
Polyketide synthase module.
 
 
0.997
pksJ
Polyketide synthase module.
 
 
0.996
tycC_2
Peptide synthetase, non-ribosomal.
 
 
0.996
grsB
Non-ribosomal peptide synthetase.
 
 
0.994
Lfee_2374
Acetyltransferase.
  
 
 0.991
Lfee_0400
Putative secreted esterase.
  
  
 0.957
psf-1
Phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily.
 
 
 0.907
metG
Methionyl tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.882
acpP_1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 0.862
acpP_2
Acyl carrier protein.
  
 
 0.854
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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