Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lfee_0402Hypothetical protein. (311 aa)    
Predicted Functional Partners:
Lfee_1823
Serine/threonine protein kinase.
    
 0.734
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 0.720
rmlA
Glucose-1-phosphate thymidylyltransferase.
   
 0.583
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.495
htpG
Class III heat-shock protein HtpG(molecular chaperone); Molecular chaperone. Has ATPase activity.
   
 0.477
crp
cNMP binding domain-containing protein.
    
  0.463
Lfee_2231
CAAX amino terminal protease family protein.
    
  0.463
Lfee_0403
EPTP domain protein.
       0.451
Lfee_2330
Inosine 5'-monophosphate dehydrogenase.
    
  0.445
yloB
Cation efflux transporter.
   
 0.444
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.