secA_1 protein (Legionella feeleii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

secA_1

Coiled-coil protein. (2864 aa)

Predicted Functional Partners:

secY

0.944

secB

0.936

secG

0.931

secE

0.924

Lfee_2374

0.894

rplW

0.836

rodZ

0.836

rpmC

0.834

polA

0.771

acpP_1

0.763

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_2374	acpP_1	Lfee_2374	Lfee_0718	Acetyltransferase.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.938
Lfee_2374	polA	Lfee_2374	Lfee_1722	Acetyltransferase.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.743
Lfee_2374	rplW	Lfee_2374	Lfee_2424	Acetyltransferase.	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	0.593
Lfee_2374	rpmC	Lfee_2374	Lfee_2430	Acetyltransferase.	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.575
Lfee_2374	secA_1	Lfee_2374	Lfee_0439	Acetyltransferase.	Coiled-coil protein.	0.894
acpP_1	Lfee_2374	Lfee_0718	Lfee_2374	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Acetyltransferase.	0.938
acpP_1	polA	Lfee_0718	Lfee_1722	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.613
acpP_1	secA_1	Lfee_0718	Lfee_0439	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Coiled-coil protein.	0.763
polA	Lfee_2374	Lfee_1722	Lfee_2374	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Acetyltransferase.	0.743
polA	acpP_1	Lfee_1722	Lfee_0718	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.613
polA	secA_1	Lfee_1722	Lfee_0439	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Coiled-coil protein.	0.771
polA	secG	Lfee_1722	Lfee_1892	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Protein-export membrane protein secG (preprotein translocase subunit); Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family.	0.503
polA	secY	Lfee_1722	Lfee_2442	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.406
rodZ	rplW	Lfee_3095	Lfee_2424	DNA-binding protein.	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	0.877
rodZ	rpmC	Lfee_3095	Lfee_2430	DNA-binding protein.	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.877
rodZ	secA_1	Lfee_3095	Lfee_0439	DNA-binding protein.	Coiled-coil protein.	0.836
rplW	Lfee_2374	Lfee_2424	Lfee_2374	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Acetyltransferase.	0.593
rplW	rodZ	Lfee_2424	Lfee_3095	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	DNA-binding protein.	0.877
rplW	rpmC	Lfee_2424	Lfee_2430	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.	0.999
rplW	secA_1	Lfee_2424	Lfee_0439	50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	Coiled-coil protein.	0.836