Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Lfee_0448Ras family GTPase. (210 aa)    
Predicted Functional Partners:
Lfee_0449
Ankyrin repeat protein.
 
 
  0.829
Lfee_2398
Serine carboxypeptidase.
  
 
 
 0.818
ralF
RalF protein, translocated into host cells by the Dot/Icm system.
 
     0.773
Lfee_2405
Serine carboxypeptidase.
  
 
   0.744
Lfee_1823
Serine/threonine protein kinase.
    
 0.734
Lfee_0405
Ectonucleoside triphosphate diphosphohydrolase.
  
     0.729
apaH
Bis(5'-nucleosyl)-tetraphosphatase; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 0.720
Lfee_0384
Ectonucleoside triphosphate diphosphohydrolase I.
  
     0.670
DWF
7-dehydrocholesterol reductase.
  
 
  0.655
Lfee_2486
Ankyrin repeat-containing protein.
  
 
  0.625
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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