Lfee_0518 protein (Legionella feeleii) - STRING interaction network

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Lfee_0518

NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (392 aa)

Predicted Functional Partners:

mdh

0.882

frmC

0.856

fumC

0.854

sfcA_1

0.847

mao2

0.847

sfcA_2

0.847

accC_2

0.841

cfiA_1

0.841

korA

0.774

Lfee_0057

0.711

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0057	Lfee_0518	Lfee_0057	Lfee_0518	SMP-30/Gluconolaconase/LRE-like region.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.711
Lfee_0518	Lfee_0057	Lfee_0518	Lfee_0057	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	SMP-30/Gluconolaconase/LRE-like region.	0.711
Lfee_0518	accC_2	Lfee_0518	Lfee_0631	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Pyruvate carboxylase subunit A.	0.841
Lfee_0518	cfiA_1	Lfee_0518	Lfee_1181	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Oxaloacetate decarboxylase subunit alpha.	0.841
Lfee_0518	frmC	Lfee_0518	Lfee_2333	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.	0.856
Lfee_0518	fumC	Lfee_0518	Lfee_1784	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.	0.854
Lfee_0518	korA	Lfee_0518	Lfee_2569	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.774
Lfee_0518	mao2	Lfee_0518	Lfee_2792	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Malate oxidoreductase.	0.847
Lfee_0518	mdh	Lfee_0518	Lfee_1167	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.	0.882
Lfee_0518	sfcA_1	Lfee_0518	Lfee_1408	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Malate dehydrogenase.	0.847
Lfee_0518	sfcA_2	Lfee_0518	Lfee_3220	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Malate dehydrogenase.	0.847
accC_2	Lfee_0518	Lfee_0631	Lfee_0518	Pyruvate carboxylase subunit A.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.841
accC_2	cfiA_1	Lfee_0631	Lfee_1181	Pyruvate carboxylase subunit A.	Oxaloacetate decarboxylase subunit alpha.	0.995
accC_2	korA	Lfee_0631	Lfee_2569	Pyruvate carboxylase subunit A.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.895
accC_2	mao2	Lfee_0631	Lfee_2792	Pyruvate carboxylase subunit A.	Malate oxidoreductase.	0.844
accC_2	mdh	Lfee_0631	Lfee_1167	Pyruvate carboxylase subunit A.	Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.	0.851
accC_2	sfcA_1	Lfee_0631	Lfee_1408	Pyruvate carboxylase subunit A.	Malate dehydrogenase.	0.844
accC_2	sfcA_2	Lfee_0631	Lfee_3220	Pyruvate carboxylase subunit A.	Malate dehydrogenase.	0.844
cfiA_1	Lfee_0518	Lfee_1181	Lfee_0518	Oxaloacetate decarboxylase subunit alpha.	NAD+-dependent formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.841
cfiA_1	accC_2	Lfee_1181	Lfee_0631	Oxaloacetate decarboxylase subunit alpha.	Pyruvate carboxylase subunit A.	0.995

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