Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
parB_2Chromosome partitioning protein ParB; Belongs to the ParB family. (262 aa)    
Predicted Functional Partners:
parA_1
Chromosome partitioning protein ParA.
 
 
 0.888
parA_3
Sporulation initiation inhibitor protein Soj.
 
 
 0.888
parA_4
Chromosome partitioning protein ParA.
 
 
 0.879
parA_2
Chromosome partitioning protein ParA.
 
   0.878
parA_5
Sporulation initiation inhibitor protein Soj.
 
   0.877
ftsK
Cell division protein FtsK.
  
   
 0.752
gidB
Glucose inhibited division protein B GidB; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
  
  
 0.641
Lfee_0556
Dot/Icm secretion system substrate.
       0.516
xerC_2
Hypothetical protein; Belongs to the 'phage' integrase family.
  
    0.511
topA_1
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.470
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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