STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
accC_2Pyruvate carboxylase subunit A. (472 aa)    
Predicted Functional Partners:
cfiA_1
Oxaloacetate decarboxylase subunit alpha.
 0.995
Lfee_0762
Acetyl/propionyl-CoA carboxylase, beta subunit.
 
 0.988
accD
Acetyl CoA carboxylase carboxyltransferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 0.910
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
 0.895
accA
acetyl-CoA carboxylase carboxyl transferase subunit Alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.884
pdhB_2
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 0.862
acsB
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.861
aceF
Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
  0.857
gltA
Citrate synthase; Belongs to the citrate synthase family.
   
 
 0.856
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
   
 
 0.856
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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