Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Lfee_0680Cation efflux system protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (400 aa)    
Predicted Functional Partners:
Lfee_0681
Permease.
 
     0.967
macB_1
Fused transporter subunits of ABC superfamily: ATP-binding component.
 
    0.967
tolC_2
Outer membrane protein TolC.
   
  0.706
bepC
Agglutination protein.
   
  0.706
Lfee_1633
Multidrug efflux protein, outer membrane component.
   
  0.706
tolC_1
Outer membrane efflux protein.
   
  0.706
acrA_2
Membrane-fusion protein AcrA.
  
  
  0.608
bepF_2
Hemolysin D; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.598
acrA
Acriflavin resistance protein E; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
  0.540
Lfee_1634
RND efflux membrane fusion protein.
     
  0.540
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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