bcr_1 protein (Legionella feeleii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

bcr_1

Multidrug resistance protein D. (395 aa)

Predicted Functional Partners:

bcr_2

0.773

anmK

0.752

garP_1

0.699

Lfee_0728

0.486

Lfee_0724

0.450

pdhB_2

0.436

trpE

0.413

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0724	bcr_1	Lfee_0724	Lfee_0725	Hypothetical protein.	Multidrug resistance protein D.	0.450
Lfee_0728	anmK	Lfee_0728	Lfee_0726	Phosphoribosyltransferase.	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.671
Lfee_0728	bcr_1	Lfee_0728	Lfee_0725	Phosphoribosyltransferase.	Multidrug resistance protein D.	0.486
Lfee_0728	garP_1	Lfee_0728	Lfee_0727	Phosphoribosyltransferase.	Major facilitator family transporter.	0.773
anmK	Lfee_0728	Lfee_0726	Lfee_0728	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	Phosphoribosyltransferase.	0.671
anmK	bcr_1	Lfee_0726	Lfee_0725	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	Multidrug resistance protein D.	0.752
anmK	garP_1	Lfee_0726	Lfee_0727	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	Major facilitator family transporter.	0.810
bcr_1	Lfee_0724	Lfee_0725	Lfee_0724	Multidrug resistance protein D.	Hypothetical protein.	0.450
bcr_1	Lfee_0728	Lfee_0725	Lfee_0728	Multidrug resistance protein D.	Phosphoribosyltransferase.	0.486
bcr_1	anmK	Lfee_0725	Lfee_0726	Multidrug resistance protein D.	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.752
bcr_1	bcr_2	Lfee_0725	Lfee_1093	Multidrug resistance protein D.	Major facilitator superfamily (MFS) transporter.	0.773
bcr_1	garP_1	Lfee_0725	Lfee_0727	Multidrug resistance protein D.	Major facilitator family transporter.	0.699
bcr_1	pdhB_2	Lfee_0725	Lfee_1854	Multidrug resistance protein D.	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	0.436
bcr_1	trpE	Lfee_0725	Lfee_0942	Multidrug resistance protein D.	Anthranilate synthase.	0.413
bcr_2	bcr_1	Lfee_1093	Lfee_0725	Major facilitator superfamily (MFS) transporter.	Multidrug resistance protein D.	0.773
garP_1	Lfee_0728	Lfee_0727	Lfee_0728	Major facilitator family transporter.	Phosphoribosyltransferase.	0.773
garP_1	anmK	Lfee_0727	Lfee_0726	Major facilitator family transporter.	anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.	0.810
garP_1	bcr_1	Lfee_0727	Lfee_0725	Major facilitator family transporter.	Multidrug resistance protein D.	0.699
pdhB_2	bcr_1	Lfee_1854	Lfee_0725	2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.	Multidrug resistance protein D.	0.436
trpE	bcr_1	Lfee_0942	Lfee_0725	Anthranilate synthase.	Multidrug resistance protein D.	0.413