Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mvaBhydroxymethylglutaryl-CoA lyase. (301 aa)    
Predicted Functional Partners:
echA8_3
enoyl-CoA hydratase.
 
 0.996
mccA
Acyl CoA carboxylase subunit alpha.
 
 
 0.976
Lfee_0762
Acetyl/propionyl-CoA carboxylase, beta subunit.
 
 0.971
atoB
Acyl CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
  0.959
acsA
acetyl-CoA synthetase.
 
 
 0.933
Lfee_0373
Enoyl-CoA hydratase/carnithine racemase.
  
 
 0.907
leuC
Aconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.900
leuD
Aconitate hydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
 
 0.898
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.884
yfcY
beta-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
  0.880
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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