minD protein (Legionella feeleii) - STRING interaction network

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Score

minD

Septum site-determining protein (cell division inhibitor). (276 aa)

Predicted Functional Partners:

minE

0.998

minC

0.998

mreC

0.795

mreD

0.793

mreB

0.544

guaA

0.503

guaB

0.491

tadA

0.489

rlmB

0.449

Lfee_0951

0.411

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0951	minD	Lfee_0951	Lfee_0953	Drug/transporter permease.	Septum site-determining protein (cell division inhibitor).	0.411
Lfee_0951	minE	Lfee_0951	Lfee_0952	Drug/transporter permease.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.411
guaA	guaB	Lfee_0955	Lfee_0954	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	minD	Lfee_0955	Lfee_0953	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Septum site-determining protein (cell division inhibitor).	0.503
guaA	minE	Lfee_0955	Lfee_0952	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.489
guaA	tadA	Lfee_0955	Lfee_0956	GMP synthase; Catalyzes the synthesis of GMP from XMP.	tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.906
guaB	guaA	Lfee_0954	Lfee_0955	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.999
guaB	minD	Lfee_0954	Lfee_0953	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Septum site-determining protein (cell division inhibitor).	0.491
guaB	minE	Lfee_0954	Lfee_0952	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.521
guaB	tadA	Lfee_0954	Lfee_0956	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.860
minC	minD	Lfee_3087	Lfee_0953	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Septum site-determining protein (cell division inhibitor).	0.998
minC	minE	Lfee_3087	Lfee_0952	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.839
minC	mreB	Lfee_3087	Lfee_2886	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape determining protein MreB.	0.622
minC	mreC	Lfee_3087	Lfee_2885	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.	0.871
minC	mreD	Lfee_3087	Lfee_2884	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape-determining protein MreD.	0.890
minD	Lfee_0951	Lfee_0953	Lfee_0951	Septum site-determining protein (cell division inhibitor).	Drug/transporter permease.	0.411
minD	guaA	Lfee_0953	Lfee_0955	Septum site-determining protein (cell division inhibitor).	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.503
minD	guaB	Lfee_0953	Lfee_0954	Septum site-determining protein (cell division inhibitor).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.491
minD	minC	Lfee_0953	Lfee_3087	Septum site-determining protein (cell division inhibitor).	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	0.998
minD	minE	Lfee_0953	Lfee_0952	Septum site-determining protein (cell division inhibitor).	Septum formation topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.998