pyrH protein (Legionella feeleii) - STRING interaction network

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pyrH

Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (247 aa)

Predicted Functional Partners:

frr

0.989

tsf

0.987

rpsB

0.980

upp

0.973

ndk

0.967

pyrF

0.946

udk_1

0.884

surE

0.870

guaA

0.856

Lfee_0179

0.855

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0179	pyrF	Lfee_0179	Lfee_2982	Uridine/cytidine kinase.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.845
Lfee_0179	pyrH	Lfee_0179	Lfee_0963	Uridine/cytidine kinase.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.855
Lfee_0179	surE	Lfee_0179	Lfee_3217	Uridine/cytidine kinase.	Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.844
Lfee_0179	udk_1	Lfee_0179	Lfee_2256	Uridine/cytidine kinase.	Uridine kinase.	0.843
Lfee_0179	upp	Lfee_0179	Lfee_2367	Uridine/cytidine kinase.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.943
frr	guaA	Lfee_0964	Lfee_0955	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.719
frr	pyrH	Lfee_0964	Lfee_0963	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.989
frr	rpsB	Lfee_0964	Lfee_0961	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.997
frr	tsf	Lfee_0964	Lfee_0962	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.998
guaA	frr	Lfee_0955	Lfee_0964	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	0.719
guaA	ndk	Lfee_0955	Lfee_3092	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.672
guaA	pyrF	Lfee_0955	Lfee_2982	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.682
guaA	pyrH	Lfee_0955	Lfee_0963	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.856
guaA	rpsB	Lfee_0955	Lfee_0961	GMP synthase; Catalyzes the synthesis of GMP from XMP.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.760
guaA	surE	Lfee_0955	Lfee_3217	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.946
guaA	tsf	Lfee_0955	Lfee_0962	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.663
guaA	upp	Lfee_0955	Lfee_2367	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.696
ndk	guaA	Lfee_3092	Lfee_0955	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.672
ndk	pyrH	Lfee_3092	Lfee_0963	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.967
ndk	rpsB	Lfee_3092	Lfee_0961	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.949