Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
pilZType IV pilus assembly PilZ. (185 aa)    
Predicted Functional Partners:
cph2_4
Regulatory protein (GGDEF and EAL domains).
  
 
 0.914
Lfee_1599
GGDEF domain-containing sensory box protein.
  
 
 0.914
fliD
Flagellar hook associated protein 2 FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.858
fliS
Flagellar protein FliS.
 
  
 0.850
flgK
Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
 
  
 0.802
Lfee_0745
Hypothetical protein.
 
     0.777
fliJ
Flagellar protein FliJ.
 
    0.775
Lfee_2672
Type II/III secretion system protein.
  
     0.768
iraA_1
Small-molecule methyltransferase IraA.
  
     0.764
Lfee_0540
Ankyrin repeats (3 copies).
  
     0.763
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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