pilZ protein (Legionella feeleii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

pilZ

Type IV pilus assembly PilZ. (185 aa)

Predicted Functional Partners:

fliD

0.873

fliS

0.852

cph2_4

0.843

Lfee_1599

0.843

flgK

0.788

fliJ

0.785

Lfee_0745

0.770

Lfee_2672

0.768

iraA_1

0.764

Lfee_0540

0.763

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lfee_0540	Lfee_0745	Lfee_0540	Lfee_0745	Ankyrin repeats (3 copies).	Hypothetical protein.	0.759
Lfee_0540	Lfee_2672	Lfee_0540	Lfee_2672	Ankyrin repeats (3 copies).	Type II/III secretion system protein.	0.761
Lfee_0540	fliJ	Lfee_0540	Lfee_3026	Ankyrin repeats (3 copies).	Flagellar protein FliJ.	0.752
Lfee_0540	iraA_1	Lfee_0540	Lfee_1084	Ankyrin repeats (3 copies).	Small-molecule methyltransferase IraA.	0.774
Lfee_0540	pilZ	Lfee_0540	Lfee_1018	Ankyrin repeats (3 copies).	Type IV pilus assembly PilZ.	0.763
Lfee_0745	Lfee_0540	Lfee_0745	Lfee_0540	Hypothetical protein.	Ankyrin repeats (3 copies).	0.759
Lfee_0745	Lfee_2672	Lfee_0745	Lfee_2672	Hypothetical protein.	Type II/III secretion system protein.	0.760
Lfee_0745	fliJ	Lfee_0745	Lfee_3026	Hypothetical protein.	Flagellar protein FliJ.	0.636
Lfee_0745	iraA_1	Lfee_0745	Lfee_1084	Hypothetical protein.	Small-molecule methyltransferase IraA.	0.754
Lfee_0745	pilZ	Lfee_0745	Lfee_1018	Hypothetical protein.	Type IV pilus assembly PilZ.	0.770
Lfee_1599	cph2_4	Lfee_1599	Lfee_0829	GGDEF domain-containing sensory box protein.	Regulatory protein (GGDEF and EAL domains).	0.995
Lfee_1599	flgK	Lfee_1599	Lfee_1479	GGDEF domain-containing sensory box protein.	Flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.	0.970
Lfee_1599	fliD	Lfee_1599	Lfee_3145	GGDEF domain-containing sensory box protein.	Flagellar hook associated protein 2 FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.	0.847
Lfee_1599	fliS	Lfee_1599	Lfee_3144	GGDEF domain-containing sensory box protein.	Flagellar protein FliS.	0.898
Lfee_1599	pilZ	Lfee_1599	Lfee_1018	GGDEF domain-containing sensory box protein.	Type IV pilus assembly PilZ.	0.843
Lfee_2672	Lfee_0540	Lfee_2672	Lfee_0540	Type II/III secretion system protein.	Ankyrin repeats (3 copies).	0.761
Lfee_2672	Lfee_0745	Lfee_2672	Lfee_0745	Type II/III secretion system protein.	Hypothetical protein.	0.760
Lfee_2672	fliJ	Lfee_2672	Lfee_3026	Type II/III secretion system protein.	Flagellar protein FliJ.	0.676
Lfee_2672	iraA_1	Lfee_2672	Lfee_1084	Type II/III secretion system protein.	Small-molecule methyltransferase IraA.	0.765
Lfee_2672	pilZ	Lfee_2672	Lfee_1018	Type II/III secretion system protein.	Type IV pilus assembly PilZ.	0.768