Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sspA_1Glutathione S-transferase (maleylacetoacetate isomerase). (209 aa)    
Predicted Functional Partners:
Lfee_1028
Fumarylacetoacetate hydrolase.
 
 
 0.996
hmgA
Homogentisate 1,2-dioxygenase.
 
 
 0.994
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.987
phhA
Phenylalanine-4-hydroxylase.
 
  
 0.816
sspA
Stringent starvation protein A.
  
 
 
0.816
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.788
rpoD
RNA polymerase sigma 70 factor (RpoD); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.775
Lfee_1030
SAM-dependent O-methyltransferase.
   
   0.765
ldh
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
       0.698
ugpQ
Glycerophosphoryl diester esterase.
  
    0.640
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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