STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lfee_1028Fumarylacetoacetate hydrolase. (332 aa)    
Predicted Functional Partners:
sspA_1
Glutathione S-transferase (maleylacetoacetate isomerase).
 
 
 0.978
lly
4-hydroxyphenylpyruvate dioxygenase.
 
  
 0.969
hmgA
Homogentisate 1,2-dioxygenase.
  
  
 0.888
phhA
Phenylalanine-4-hydroxylase.
 
  
 0.703
hpcD
5-carboxymethyl-2-hydroxymuconate Delta-isomerase.
  
 
 0.680
Lfee_1030
SAM-dependent O-methyltransferase.
     
 0.649
fadH
2,4-dienoyl-CoA reductase FadH1.
    
 0.649
ldh
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
 
  
 0.638
fumC
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 0.633
sdhA
Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.623
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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