Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ampHAMPC cephalosporinase. (388 aa)    
Predicted Functional Partners:
Lfee_1719
(serine-type) D-alanyl-D-alanine carboxypeptidase.
  
     0.734
pbpE_2
Beta-lactamase.
  
     0.654
Lfee_1056
Hypothetical protein.
       0.544
Lfee_0011
Putative secreted esterase.
  
     0.465
ftsI
Peptidoglycan synthetase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
     
 0.464
mrdA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
     
 0.462
dacB
D-Ala-D-Ala carboxypeptidase.
     
 0.461
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.454
dacA
D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Belongs to the peptidase S11 family.
     
 0.421
Lfee_1057
Glutamate synthetase.
       0.409
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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