STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spsEN-acetylneuraminic acid synthetase. (361 aa)    
Predicted Functional Partners:
neuA
CMP-N-acetlyneuraminic acid synthetase.
 
 0.997
neuC
N-acylglucosamine 2-epimerase.
 
 
 0.994
rmlA
Glucose-1-phosphate thymidylyltransferase.
 
  
 0.962
yvfE
Cell wall biosynthesis regulatory pyridoxal phosphate-dependent protein; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.947
strE
NAD dependent epimerase/dehydratase family protein.
 
    0.946
dapH
Chloramphenicol acetyltransferase.
 
     0.926
Lfee_1074
LPS biosynthesis protein.
 
 
   0.830
kdsC
Hydrolase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
 0.784
phaB_2
Acetyoacetyl CoA reductase.
 
    0.661
hemL_2
Putative aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
     0.598
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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