STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
spsEN-acetylneuraminic acid synthetase. (361 aa)    
Predicted Functional Partners:
neuA
CMP-N-acetlyneuraminic acid synthetase.
 
 0.998
neuC
N-acylglucosamine 2-epimerase.
 
 
 0.994
rmlA
Glucose-1-phosphate thymidylyltransferase.
 
 
 0.980
strE
NAD dependent epimerase/dehydratase family protein.
 
    0.948
yvfE
Cell wall biosynthesis regulatory pyridoxal phosphate-dependent protein; Belongs to the DegT/DnrJ/EryC1 family.
 
  
 0.944
dapH
Chloramphenicol acetyltransferase.
 
     0.929
Lfee_1074
LPS biosynthesis protein.
 
 
   0.827
kdsC
Hydrolase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
 0.730
hisH1
Putative imidazole glycerol phosphate synthase,glutamine amidotransferase subunit (HisH); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.691
phaB_2
Acetyoacetyl CoA reductase.
 
     0.667
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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