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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Lfee_1074LPS biosynthesis protein. (391 aa)    
Predicted Functional Partners:
hisF_2
Putative imidazole glycerol phosphate synthase,cyclase subunit (HisF); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
   0.872
cysE
Serine acetyltransferase.
 
  
 0.860
hisH1
Putative imidazole glycerol phosphate synthase,glutamine amidotransferase subunit (HisH); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
    0.834
spsE
N-acetylneuraminic acid synthetase.
 
 
   0.827
phaB_2
Acetyoacetyl CoA reductase.
 
     0.793
neuA
CMP-N-acetlyneuraminic acid synthetase.
 
     0.777
hemL_2
Putative aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
     0.772
neuC
N-acylglucosamine 2-epimerase.
 
    0.751
rmlA
Glucose-1-phosphate thymidylyltransferase.
 
 
  0.738
strE
NAD dependent epimerase/dehydratase family protein.
 
   0.651
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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