tdcG protein (Legionella feeleii) - STRING interaction network

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Score

tdcG

L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)

Predicted Functional Partners:

glyA

0.936

psdht

0.869

metB

0.862

trpA

0.861

tdcB

0.844

pssA

0.843

gloA

0.843

trpB

0.843

mip

0.720

ampG_1

0.720

Your Current Organism:

Legionella feeleii

NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ampG_1	mip	Lfee_1096	Lfee_1095	Beta lactamase induction signal transducer AmpG.	Macrophage infectivity potentiator (Mip).	0.758
ampG_1	tdcG	Lfee_1096	Lfee_1094	Beta lactamase induction signal transducer AmpG.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.720
gloA	psdht	Lfee_1740	Lfee_1208	Lactoylglutathione lyase.	Phenylserine dehydratase.	0.495
gloA	tdcB	Lfee_1740	Lfee_0990	Lactoylglutathione lyase.	L-threonine dehydratase catabolic TdcB.	0.495
gloA	tdcG	Lfee_1740	Lfee_1094	Lactoylglutathione lyase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.843
gloA	trpA	Lfee_1740	Lfee_3197	Lactoylglutathione lyase.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.843
gloA	trpB	Lfee_1740	Lfee_3198	Lactoylglutathione lyase.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.854
glyA	psdht	Lfee_0067	Lfee_1208	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Phenylserine dehydratase.	0.867
glyA	pssA	Lfee_0067	Lfee_1191	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	CDP-diacylglycerol-serine O-phosphatidyltransferase (phosphatidylserine synthase); Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.843
glyA	tdcB	Lfee_0067	Lfee_0990	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-threonine dehydratase catabolic TdcB.	0.841
glyA	tdcG	Lfee_0067	Lfee_1094	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.936
glyA	trpA	Lfee_0067	Lfee_3197	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.	0.865
glyA	trpB	Lfee_0067	Lfee_3198	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.	0.865
metB	psdht	Lfee_0190	Lfee_1208	Cystathionine beta-lyase.	Phenylserine dehydratase.	0.864
metB	tdcB	Lfee_0190	Lfee_0990	Cystathionine beta-lyase.	L-threonine dehydratase catabolic TdcB.	0.796
metB	tdcG	Lfee_0190	Lfee_1094	Cystathionine beta-lyase.	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.862
mip	ampG_1	Lfee_1095	Lfee_1096	Macrophage infectivity potentiator (Mip).	Beta lactamase induction signal transducer AmpG.	0.758
mip	tdcG	Lfee_1095	Lfee_1094	Macrophage infectivity potentiator (Mip).	L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.	0.720
psdht	gloA	Lfee_1208	Lfee_1740	Phenylserine dehydratase.	Lactoylglutathione lyase.	0.495
psdht	glyA	Lfee_1208	Lfee_0067	Phenylserine dehydratase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.867