| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lfee_2368 | ribBA | Lfee_2368 | Lfee_2369 | Putative biotin synthetase like protein. | GTP cyclohydrolase II. | 0.995 |
| Lfee_2368 | ribD | Lfee_2368 | Lfee_1118 | Putative biotin synthetase like protein. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.916 |
| Lfee_2368 | ribE | Lfee_2368 | Lfee_1117 | Putative biotin synthetase like protein. | Riboflavin synthase subunit alpha. | 0.828 |
| Lfee_2368 | ribH | Lfee_2368 | Lfee_1115 | Putative biotin synthetase like protein. | Riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.820 |
| kdsA | pyrG | Lfee_1113 | Lfee_1114 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.873 |
| kdsA | ribA | Lfee_1113 | Lfee_1116 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.705 |
| kdsA | ribD | Lfee_1113 | Lfee_1118 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.724 |
| kdsA | ribE | Lfee_1113 | Lfee_1117 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Riboflavin synthase subunit alpha. | 0.696 |
| kdsA | ribH | Lfee_1113 | Lfee_1115 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.726 |
| kdsA | yggG | Lfee_1113 | Lfee_1120 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Zn-dependent protease. | 0.584 |
| map_2 | ribE | Lfee_2918 | Lfee_1117 | Major acid phosphatase Map (histidine-acid phosphatase). | Riboflavin synthase subunit alpha. | 0.548 |
| map_2 | ribF | Lfee_2918 | Lfee_2604 | Major acid phosphatase Map (histidine-acid phosphatase). | Riboflavin biosynthesis protein RibF (riboflavin kinase/FMN adenylyltransferase); Belongs to the ribF family. | 0.548 |
| pyrG | kdsA | Lfee_1114 | Lfee_1113 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.873 |
| pyrG | ribA | Lfee_1114 | Lfee_1116 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.709 |
| pyrG | ribD | Lfee_1114 | Lfee_1118 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.701 |
| pyrG | ribE | Lfee_1114 | Lfee_1117 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Riboflavin synthase subunit alpha. | 0.696 |
| pyrG | ribH | Lfee_1114 | Lfee_1115 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.744 |
| pyrG | yggG | Lfee_1114 | Lfee_1120 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | Zn-dependent protease. | 0.584 |
| ribA | kdsA | Lfee_1116 | Lfee_1113 | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.705 |
| ribA | pyrG | Lfee_1116 | Lfee_1114 | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.709 |