Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ptsNNitrogen regulatory protein. (158 aa)    
Predicted Functional Partners:
ptsH
Sugar transport PTS system phosphocarrier HPr protein.
 
 
 0.994
yhbH
Ribosome-associated, sigma 54 modulation protein.
  
  
 0.942
ptsP
Phosphoenolpyruvate-protein phosphotransferase PtsP; Belongs to the PEP-utilizing enzyme family.
  
   
 0.845
rpoN
RNA polymerase sigma-54 factor (sigma-L); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.785
cpsB
Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.583
tdh
Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
  
 
  0.558
Lfee_0127
Sigma 54 modulation protein YhbH.
  
  
 0.548
iolCB
IolC/IolB transferase kinase protein; Belongs to the carbohydrate kinase PfkB family.
    
 0.530
Lfee_1773
Putative helicase/relaxase.
     
 0.490
chiD
Chitinase.
     
 0.477
Your Current Organism:
Legionella feeleii
NCBI taxonomy Id: 453
Other names: ATCC 35072, CCUG 16417, CIP 103877, DSM 17645, L. feeleii, NCTC 12022, strain WO-44C
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